בעקבות תחקיר ''ידיעות אחרונות'': ''דן'' לא תפרסם קמפיין של הגוף שמתנגד לחיסון הילדים  

Geert Vanden Bossche, PhD, DVM

Profile: Experienced management professional; expert in vaccine R&D and early vaccine dvpt,; proficiency in program and grant management; used to working in a heavily interconnected environment (in private and nonprofit sector) while managing the needs of numerous stakeholders.

Proven track record of success in designing and developing vaccines, managing dynamic, high-performing consortia, developing efficient processes to deliver impact, offering expert scientific-technical advice on complex immunisation projects, leading vaccine R&D work as CSO.

Proficiency in program management, team leadership, patent writing, laboratory research, immunology, epidemiology, microbiology, vaccine technologies, preclinical vaccine dvpt. Substantial experience in strategic budgeting, CMC- and IP-related matters, incl.

patent infringement and litigations. Over 2 decades of professional experience working in Europe and the US in managing implementation of immune interventions to address unmet medical needs. Highly familiar with major challenges in Global Health (as previously engaged with B. & M. Gates Foundation and GAVI).

I am particularly interested in engaging with international companies or organisations in the private or public sector or which are involved in public-private partnerships targeted at translational medicine programs, preferably in the field of Vaccine Innovation or Intellectual Property (e.g., IP issues, litigations related to infringement of vaccine patents).

Experience

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Mar 2018 - Present 3 years 9 months

3040 Huldenberg

VARECO Graphic

Managing Director

VARECO

Sep 2012 - 2019 7 years

Europe

Independent vaccine consultant with a long- standing track record in Academia, Vaccine Industry and Global Health (GH); providing support on vaccine project management as well as advice, guidance and expert opinion on preclinical development of vaccines & biologicals, from project selection up to IND.

Assignments include prophylactic and therapeutic vaccine projects in Human and Veterinary Vaccine Industry, Small Biotech, Global Health organizations in the US or Europe

My knowledge, insights and skills cover a diversified spectrum of Life Science domains including:

- Life Science Project Management (in early and late dvpt)

- Due diligence on technologies & processes related to vaccines, adjuvants and biologicals

- Patent writing and strategic IP management

- Guidance on regulatory requirements to CMC documentation, DMF files

- Target product profiling and SWOT analysis

- Infectious and immune-mediated diseases including their (immune) pathogenesis and epidemiology

- Host-pathogen interactions and mechanisms of immune escape

- Innate and adaptive immunology (both, humoral and cell-mediated)

- Antigen discovery

- Preclinical vaccine development (including animal experimentation as well as immunological

and physicochemical characterization of vaccines and biologicals)
- Vaccine formulation science and modern vaccine delivery technologies (incl. devices); modern technologies for enhancement of antimicrobicidal activity in multidose vaccines

- Small-scale pre-GMP vaccine manufacturing (incl. synthetic chemistry of Ag or adjuvant, recombinant Ag expression, viral vectors, upstream and downstream processing)

To enhance the quality and capacity of my consultancy services, I leverage an extensive network of professional contacts providing direct access to US and European governmental and regulatory agencies, Academia and Research Institutions, Human and Veterinary Vaccine Industry, Global & Public Health organizations and CROs in the US and Europe

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German Centre for Infection Research (DZIF) Graphic

Head of the Vaccine Development Office

German Centre for Infection Research (DZIF)

Aug 2017 - Dec 2017 5 months

Cologne, Germany

Spearheading a portfolio of translational vaccine research projects, conducted at German universities and research centres sponsored by DZIF. Holding overall accountability for strategic alignment of translational infection research in support of preclinical and early clinical testing.

 Developing a trans-academic translational network for Vaccine development totalling eight universities and research organizations across Germany.

Univac Graphic

Chief Innovation & Scientific Officer

Univac

Nov 2014 - Nov 2016 2 years 1 month

Huldenberg

II founded Univac as inventor of a new vaccine technology which I subsequently further developed as CSO of the Company. The technology enables the development of universal vaccines educating the host immune system to redirect immune targeting away from canonical antigens to a widely divergent spectrum of vitally vulnerable pathogen-derived ‘self-mimicking’ antigens, irrespective of MHC polymorphism. Although ‘non-self’ and exposed on the surface of infected or pathologically altered cells…

Global Alliance for Vaccines and Immunisation (GAVI) Graphic

Program Manager

Global Alliance for Vaccines and Immunisation (GAVI)

Mar 2015 - Mar 2016 1 year 1 month

Geneva Area, Switzerland

During my term at GAVI, I coordinated GAVI’s Ebola Vaccine Program and contributed to the implementation of an integrated vaccine work plan in collaboration with Global Health Partners (WHO, Bill & Melinda Gates Foundation, CDC, UNICEF), regulators (FDA) and vaccine manufacturers to enable timely deployment or stockpiling of Ebola vaccine candidate(s) that suitably meet the requirements for use in an Ebola epidemic. In this capacity, I also contributed to several workshops aimed at proposing…

Positions in Academia Graphic

DVM, PhD, adjunct professor

Positions in Academia

Sep 1980 - Sep 20153 5 years 1 month

Belgium - Germany

- Training in Veterinary Medicine at the faculty Notre-Dame-de-la-Paix and the State University of
Ghent (1980-1983)

- Doctoral degree in Veterinary Medicine from State University of Ghent (1983)

- Postdoctoral training in Equine Medicine and Surgery at the Free University of Berlin, Germany
(1984-1987)

- Postdoctoral Fellowship in Virology at James A. Baker Institute for Animal Health, Cornell University, Ithaca, NY 14850, USA (Sept 1990- mid 1991)
- Research…

Bill & Melinda Gates Foundation (BMGF) Graphic

Senior Program Officer, Global Health, Vaccine Discovery

Bill & Melinda Gates Foundation (BMGF)

May 2008 - Jun 2011 3 years 2 months

Seattle, Washington 98102, USA

Responsible for operating Vaccine Programs (e.g., HIV-1, Malaria, TB, Polio...) and establishing international product development partnerships for immune interventions in Global Health (e.g., with Academia, Biotech Industry, NIH, Welcome Trust, WHO, PATH).

Coordinating and spearheading international collaborations and consortia on innovative vaccine approaches and steering multidisciplinary vaccine initiatives

Solvay Biologicals Graphic

Global Project Director Influenza Vaccines

Solvay Biologicals

Jul 2007 - May 2008 11 months

Weesp, the Netherlands

Responsible for leading the operational aspects of an interdisciplinary project team including the planning and implementation of adjuvanted Influenza vaccines that enable dose sparing.

Implementation of commercial-scale production of cell-based methods and expansion of Influenza vaccine production capacity such as to meet DHSS (U.S. Department of Human Health Services) contractual requirements (Pandemic Influenza Preparedness Plan)

Novartis Vaccines & Diagnostics Graphic

Director, Research Program Leader and Head of Adjuvants
Novartis Vaccines & Diagnostics

Aug 2006 - Jul 2007 1 year

Siena, Italy & Emeryville, USA

Vaccine Research Program/Adjuvant Program responsibilities:

- Project leader of NVD's RSV vaccine project (Respiratory Syncytial Virus)

- Coordinator of preclinical activities on combined seasonal RSV-Influenza vaccine for elderly &
high risk adults

- Responsible for defining and shaping the scope and strategy of NVD's adjuvant and vaccine

delivery technologies including management of NVD’s adjuvant portfolio, opportunity sourcing, and establishment of an internal interdisciplinary due diligence team for the evaluation of relevant
extramural opportunities.

GlaxoSmithKline Biologicals Graphic

Head of Adjuvant Technologies and Alternative Deliveries, R&D GlaxoSmithKline Biologicals

May 2001 - May 2006 5 years 1 month

Rixensart, Belgium

- Research Program Leader on Vaccine Formulation Development & Alternative Deliveries and in charge of biophysical characterization activities on adjuvanted vaccine formulations.

- Coordination and follow-up of extramural contracts & collaboration agreements on new immunization strategies and innovative vaccine adjuvant, delivery or formulation technologies (e.g., co-delivery, mucosal, subcutaneous, intradermal immunization)

- Development and validation of vaccine and adjuvant characterization assays

- Study of adjuvant-antigen interaction and of adjuvant structure-function relationship

- Coordination and resource management of preclinical activities including CMC section of INDs and cGMP production of (adjuvanted) vaccine candidates

- Planning laboratory activities and establishing outside collaborations with academia

GSK Biologicals
6 years 4 months

Senior Project Leader ‘Adolescent Vaccine Projects'
Jun 1998 - May 20013 years

Rixensart, Belgium

Major responsibilities:
Project Management on Raw Material Traceability (RAMATRA) and vaccine projects in Late Development, e.g., Herpes Simplex Virus type 2, Hepatitis B, Streptococcus Pneumoniae and Enterotoxic Escherichia Coli (in collaboration with SBL Vaccines, Sweden)

New Biotech Vaccine Development and QC-QA Manager
Feb 1995 - May 19983 years 4 months

Rixensart, Belgium

Major responsibilities (3 direct reports; 6 technicians):

- Management and coordination of vaccine product development, optimization as well as validation of analytical methods in accordance with regulatory requirements or guidelines and vaccine
marketing constraints

- Budget management of all activities related to QC assay development

- Transfer from R&D and further development of new QC-relevant characterization techniques on new vaccine candidates (e.g., HSV-2 vaccine, Lyme disease vaccine); contacts with national/ international regulatory and health authorities (e.g., FDA, NIBSC, IHE, WHO,…) on technical dossiers; active participation in pre-IND meetings

Education

Ghent UniversityGhent University Graphic
Ghent University

Doctor of Medicine (M.D.)Veterinary Medicinecum Laude

1980 - 1983

Detailed CV and list of publications available on demand

St-Lievenscollege Antwerp- Belgium Graphic

https://be.linkedin.com/in/geertvandenbossche